Puzzle 120 - Solution

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 You break all the four pills into halves. And you take one half of each pill and give the other half to the guide.

Now both of you have eaten 1/2 blue pill+ 1/2 green pill + 1/2 blue pill+ 1/2 green pill i.e. 1 blue pill and 1 green pill. 

And the antidote will work. 

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